IONOVATION SCOUT

• 详细介绍
• 详细参数

• 详细介绍

  Ionovation company Ionovation scout restructuring of bilayer lipid membrane electrophysiological analysis system, is one of the latest products in this field, it overcomes the traditional patch clamp series of shortcomings, whether from the technical content of products or from the perspective of the application field of the product, in the electrophysiological analysis technology has always been in a leading position, the developing direction of the electrophysiological analysis technology, is the preferred cell electrophysiological analysis laboratory experimental apparatus at home and abroad. This highly flexible desktop detection system is adapted to a variety of experimental conditions and has been used to study cell membrane ion channels, various animal and plant transporters and their organelles.
  

  
  

  Ionovation scout technical characteristics：

  √ don't need to create a gigaom block

  √ the only way to measure the double seal

  √ can be used to detect ion channels, vesicles and ligands on various cell membranes

  √easy to carry out analysis and detection for single ion channel

  √The condition can be changed on both sides of the membrane to form a double channel for analysis              

  
  

  Technology principle:

        The Ionovation Scout USES artificial lipid membranes to construct ion channels. The system is measured using two separate electrophysiological measurement Chambers. The double chamber is separated (a) by a polytetrafluoroethylene septum (a) 25 mm thick and 120 micron in diameter. The volume of the two polycarbonate cells was 1.2ml. The polycarbonate chamber has holes at the top for easy access to Ag/AgCl electrodes and injection buffer (a). When the two Chambers are filled with the appropriate buffer, the lipids dissolved in the n-decane are dispersed into the pore (b) of the teflon diaphragm, which is 120 microns in diameter. The level of the buffer is continuously lowered and elevated until the excess lipids on the teflon diaphragm are removed, and an artificial biolipid membrane (C) is formed on the teflon diaphragm with a double layer of lipid self-tissue.  

        It is then manipulated according to specific target proteins or organelles. For example, a toxin similar to the hemolysin can be added directly to the polycarbonate chamber for testing. The recombinant ion channel needs to be combined with fatty acids to form recombinant lipoproteins, and these lipoproteins are then "cut" from the biofilm to fuse with the artificial lipid membrane by ion gradient or fusion peptide method.

  After the sample was prepared, the electrophysiology test was carried out. By applying different voltages to monitor the current in the cell's single ion channel, where the signal with a bandwidth of 5-10 kHz is stored on the system's hard drive, the test usually takes the form of voltage clamp mode, in which different voltages are applied to get the target signal.

  
  

  Application：

  1.Lipid triggers

  2.Cell membrane transport

  3.Membrane active agents such as synaptic nucleoprotein

  4.Drug safety analysis

  5.Signal transduction mode analysis

  
  

  Application case

  Ionovation Scout test system can be used for analysis of multiple ion channels:

  1. Measuring objects: accurate measurement of thousands of ion channels, transporters and pore activities can be achieved.

  2. Software: electrophysiological data collection and analysis software Patchmaster, which USES user-friendly software to realize all measurement control; User defined experimental workflow with pre-defined protocols;

  3. Automatic operation: full-automatic equipment operation (double-layer production and verification, double-layer integrity of capacitance control, film two-side perfusion system); Two layer visualization operation;

  4. Current measurement: stable low noise Ag/AgCl electrode, using salt bridge to record the current range from pA to several nA

  5. Consumables: one-time bimolecular chamber can be simply and quickly replaced;

• 详细参数

• 产品特色

  因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。

• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。