CellWave Sorter

• 详细介绍
• 详细参数

• 详细介绍

  CellWave Acoustic Microfluidic Label-Free Cell Sorting System
  CellWave is a next-generation cell sorting platform based on Acoustic Microfluidics technology. Whether you're working in cell therapy, immunology, oncology, or rare cell isolation, CellWave offers a label-free, non-invasive, high-purity cell sorting solution. It is a truly damage-free platform for cell sorting!
  Technical Advantages
  1.Non-invasive Sorting
  Cell sorting is achieved using acoustic waves, maintaining low shear force throughout the process and preserving the natural state of cells. It is particularly suitable for sensitive samples such as stem cells, extracellular vesicles (EVs), and primary cells.
  2.Ultra-high Purity and Recovery
  By precisely manipulating cells with acoustic standing wave fields, sorting purity exceeds 95%, and recovery rates exceed 80%—greatly surpassing traditional methods like FACS (Fluorescence-Activated Cell Sorting) or MACS (Magnetic-Activated Cell Sorting) in gentleness.
  3.High Throughput and Automation
  With a processing speed of up to 10⁶ cells/min, CellWave supports continuous sorting, minimizing manual errors. Integrated smart software allows one-click parameter setup, enabling easy and reproducible experiments.
  4.Versatile Compatibility
  Compatible with a variety of sample types, including blood, tissue dissociates, and cultured cells. Its modular design supports custom sorting strategies, such as sorting based on cell size, density, or mechanical properties.
  Technology Principle
  CellWave uses high-frequency ultrasound (MHz range) to generate a stable standing acoustic wave field inside a microfluidic chip. This allows non-contact manipulation of cells or particles through Acoustic Radiation Force:
  
  Standing Acoustic Wave Field
  Generated by a piezoelectric transducer, creating periodic high/low-pressure nodes inside the microchannel.
  Acoustic Radiation Force
  Cells are driven by pressure differentials in the acoustic field, migrating toward pressure nodes or antinodes, depending on their physical characteristics.
  Sorting Mechanism
  Cells of different sizes, densities, or mechanical properties respond differently to acoustic forces, enabling precise separation.
  Operation Workflow
  Sample Injection
  Cell suspensions flow through the microfluidic channel under laminar flow conditions.
  Acoustic Field Activation
  High-frequency ultrasound is activated, forming a standing wave field. Cells concentrate at pressure nodes.
  Sorting and Output
  Target cells: Deflected by acoustic forces and collected at the designated outlet.
  Non-target cells: Flow along the waste channel for removal.
  Gentle Recovery
  Sorted cells maintain high viability and are ready for direct downstream culture or analysis.
  Core Application Areas
  Cell Therapy and Regenerative Medicine
  Sorting of stem cells (e.g., CAR-T, iPSC preparation) to ensure the safety and consistency of clinical-grade cell products.
  Cancer Research and Liquid Biopsy
  Efficient enrichment of circulating tumor cells (CTCs) and extracellular vesicles, supporting early cancer screening and treatment monitoring.
  Immunology and Infectious Diseases
  Sorting of rare immune cells (e.g., antigen-specific T cells), accelerating vaccine development and immune response studies.
  Microbiology and Synthetic Biology
  High-throughput sorting of bacteria and yeast, optimizing strain selection and biomanufacturing processes.
  

  Advantages Compared to Other Sorting Technologies

  Parameters	CellWave sound wave sorting	Conventional Flow Sorting (FACS)	Magnetic bead sorting (MACS)
  Cell damage	no	Laser/voltage damage cells	Antibody labeling may activate the cells
  Labeling requirements	Not required (can be marked if the sample has special requirements)	Fluorescently labeled	Magnetic bead labeling is required
  Flux	High (continuous flow)	High (Single cell detection)	Low (Batch processing)
  Cost-effectiveness	Low initial purchase cost and simple later maintenance	The initial purchase cost is high, and the later maintenance cost of the laser is high	The initial purchase cost is high, and the later use cost of the magnetic beads is high

  
  

• 详细参数

  
  

  Classification	Parameters (English)	Parameters (Chinese)	Specifications
  Optical system	Laser	Laser wavelength	488 nm
  	Fluorescence Filter	Fluorescence filter	530/43 nm
  	Detectors	Detector	FITC (Fluorescence), FSC (forward scattering)
  Fluid systems	Sample input
  	Maximum Input Sample Volume	Maximum sample volume	600 µL
  	Minimum Input Sample Volume	Minimum sample volume	150 µL
  	Recommended Input Volume	Recommended sample volume	150-300 µL
  	Recommended Concentration	Recommended sample concentration	0.5-1.5×10⁶ cells/mL
  	Maximum Sheath Volume	Maximum sheath volume	1.2 mL
  	Max Sheath Pressure	Maximum sheath fluid pressure	5 PSI
  	Recommended Sheath Pressure	Recommend sheath pressure	2.25 PSI
  Output and Performance	Output Containers	Output containers	2×1.5 mL EP tubes
  	Throughput	Flux	10,000 cells/sec
  	Max Sample Pressure	Maximum sample pressure	2 PSI
  	Recommended Sample Pressure	Recommended sample pressure	1 PSI

  
  

• 产品特色

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• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。