Hydroporator Microfluidic Cell Transfection Platform

• 详细介绍
• 详细参数

• 详细介绍

  Basic Information
  Hydroporator is a non-viral microfluidic platform for highly effective delivery of external cargos such as plasmid DNA, mRNA, proteins, CRISPR-Cas9 RNPs, and nanoparticles into primary cells. The Hydroporator technology enables high delivery efficiency, easy operation, low cost, high scalability, minimal cell perturbation (i.e., preserved cell function and viability), and cell type/cargo insensitive delivery. Hydroporator is free from the challenges from viral transduction, lipofection and electroporation, establishing a new avenue to accelerate cancer immunotherapy, cellular engineering and genome editing.
  
  Product Advantages:
  1.Hydrodynamic flow enables efficient and gentle transfection without chemical reagents.
  2.Fully automated operation supports consistent and high-throughput experiments.
  3.Precise microfluidic control ensures uniform transfection across all cells.
  4.Compatible with various cell types and cargos including DNA, RNA, and proteins.
  5.Closed and sterile workflow minimizes contamination risk.
  6.Real-time monitoring maintains optimal transfection conditions.
  7.Compact design and intuitive interface simplify laboratory integration.
  
  Main Product Features:
  1. Broad Compatibility with Diverse Cell Types
  Hydroporator® RUO is optimized for a wide range of cells, from immortalized cell lines to hard-to-transfect primary cells and stem cells. Its hydrodynamic delivery mechanism provides high efficiency across both adherent and suspension cells.
  2. High Viability and Low Cytotoxicity
  Unlike electroporation or chemical transfection, the hydrodynamic approach maintains excellent cell viability. This makes it especially suitable for sensitive cells such as primary immune cells, neurons, and iPSCs.
  3. Efficient Delivery of Multiple Cargo Types
  The system can deliver various biomolecules — including plasmid DNA, mRNA, siRNA, proteins, and nanoparticles — into mammalian cells with high reproducibility and minimal cell stress.
  4. Optimized Protocols for Each Cell Category
  Pre-installed and customizable transfection protocols are available for different cell types. Users can quickly select the appropriate settings without tedious parameter optimization.
  5. Excellent Scalability for Research and Screening
  Hydroporator® RUO supports both small-scale validation experiments and large-scale transfection studies, making it ideal for research in gene editing, drug discovery, and cell therapy development.
  6. Consistent Results across Multiple Cell Lines
  The microfluidic control ensures uniform shear stress and flow exposure, providing reproducible transfection efficiency and expression levels across experiments and cell batches.
  
  Application Areas:
  Gene Editing
  Enables efficient delivery of CRISPR components for precise genome modification in various cell types.
  Gene Therapy
  Supports non-viral gene delivery methods for safer and reproducible therapeutic development.
  Regenerative Medicine
  Facilitates transfection of stem cells and iPSCs to study tissue repair and regeneration.
  Cell Therapy
  Delivers genes or mRNA into immune cells such as T cells for CAR-T or engineered cell therapy.
  Cell Engineering
  Provides a platform for modifying cell function through gene or protein delivery.
  Cell Line Development
  Enables stable and reproducible transfection for generation of engineered cell lines.
  CRISPR Genome Editing in T Cells
  Efficiently edits endogenous genes such as TCR and PD-1 in human T cells.
  mRNA-based CAR-T Cell Manufacturing
  Offers a non-viral method for producing mRNA-CAR-T cells with high viability.
  For research use only.
  

• 详细参数

  Specification
  Usage: For Research Use Only
  Scale: Laboratory (Research) scale
  Cell Capacity: Up to 10 million cells per run
  Delivery Efficiency: High delivery efficiency with preserved cell viability and functionality
  Protocols: Pre-loaded and adjustable protocols for various cell types and cargo
  Software: Intuitive software UI with customizable options
  Cartridge Compatibility: Compatible with HP-L and HP-S cartridges
  System Type: Fully automated system
  Reagent Requirement: No additional reagents required for processing
  Design: Compact size, ergonomically designed for optimal user environment
  Consumables: Compatible with standard laboratory consumables
  Sterility: Sterile packaging for cartridges
  Cleaning: Cleaning cartridge included

• 产品特色

  因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。

• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。