Nano-scale Temperature Controller for Single Cells and Organoids

• 详细介绍
• 详细参数

• 详细介绍

  Diamond HeaterThermometer （DHT)
  DHTIS THE ONLY TOOL WHICH COMBINESTEMPERATURE MEASUREMENT AND THERMAL STIMULATIONIN A SINGLE PARTICLE
  An elegant solution consisting of a glass capillary and a single diamondcrystal, DHT allows one to reliably induce desired level of ultra-local heating andprecisely measure temperature changes at the nanoscale.
  Thermosensitive silicon-vacancy (SiV) color centers in diamond enable purelyoptical temperature readout in the near-infrared range. No bulky electric circuitsneeded.
  Unprecedented temporal and spatial resolution allows you to implementsarbitrary thermal protocols and apply them to a variety of solid-state and biologicalsystems, from ion channels to multicellular organoids.
  Main features
  PERFORM STABLE AND RELIABLE MEASUREMENTS
  Thanks to the properties of diamond, the DHThas infinite photo stability and is insensitive to the effects of the environment (PH, magnetic orelectricfield), makingyour temperature measurements fully reliable.
  WORK IN THE BIOLOGICAL TRANSPARENT WINDOW
  The fluorescenceof the siv-centers lies in thenear-infrared,soyoucan use the DHT with any sensitive biological samples.
  CONTROL THE FASTEST PROCESSES
  DHT allows you to define custom ultra fast temperature protocols, with millisecond steps in the detection mode and microsecond for the heating.
  CHOOSE OPTIMAL DIAMONDS
  wide range of diamond particle sizes available, from 50nm upto hundreds of microns.
  
  
  core technology
  TheDHT technology is base dona single engineered diamond micro or nano particle place don the tipo fa pulled glass pipette. This diamond particle has two main features:
  1. It contains atomic defects in its crystalline lattice called silicon vacancy(siv)color centers, which act as quantum sensors and enable all optical fluorescencebased thermometry.
  2. It possesses amorphous carbon at its intercrystalline boundaries,making it an efficient light absorber and effectively turning it into an ultra-local nanoscale heat source.
  
  Example applications
  spatially-selectivethermalstimulation of single ion channel sand their clusters on living cells'membranes
  ultra-local thermal stimulation of living cells' division
  Thermal stimulation of inter-neuron al synaptic contacts formation
  Research on disease biology(e.g.Alzheimer's, parkinson's, epilepsy) through ion channel sand nano scale thermodynamics
  Thermal nano scale manipulation of calcium concentration gradients inside a living cell
  Thermal control of cytoskeletal  intracellular structures'growth, directed by microscopic thermal gradient
  ultra-local method ofthermal lethal action on individual(cancerous) cells inside living tissue
  spatially-resolved thermalaction to terminate pathological epileptic processes inside brain structures
  

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• 产品特色

  因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。

• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。