Raman Optical Activity Spectrometer

• 详细介绍
• 详细参数

• 详细介绍

  Basic Information
  The unique measurement technology was developed at ETH Zürich and measures an effect known as Raman optical activity (ROA), which has been widely studied and shown by researchers to have enormous potential for the measurement of pharmaceuticals. The wide adaptation of this measurement has been impossible before now because of the complexity of the instrumentation and the requirement for expert users. ENANTIOS’ patent-pending technology enables the full exploitation of this measurement in industry for the first time. Enantios’ chiral optical analysis technology (ROA, Raman Optical Activity) is a high-precision, non-destructive method for determining the chiral structure and stereochemical configuration of molecules. This technique allows direct analysis in solution without the need for crystallization or HPLC, making it suitable for small-molecule drugs, proteins, biosimilars, vaccine VLPs, and chiral catalysts. ROA provides detailed information on secondary and tertiary structures, monitors structural integrity and stability, and tracks chiral changes during reactions, offering reliable data for drug development, quality control, vaccine validation, and catalyst optimization.
  Product Advantages:
  Chiral Small Molecules:
  Absolute configuration
  Isomeric/enantiomeric excess
  No crystallization or HPLC required!
  Biologics:
  Secondary and tertiary structural motifs
  Structural stability and degradation testing
  Measurement in solution!
  RAMAN VS. ROA：Raman scattering identifies the molecular fingerprint- but is blind to chirality (handedness). ROA can differentiate between enantiomers, determine enantiomeric excess and look at chiral structures of proteins and biologics.
  
  Main Product Features:
  
  Application Areas:
  Chiral drug R&D and quality control: Used to determine the absolute configuration and enantiomeric excess of chiral drugs such as ibuprofen, without crystallization or High-Performance Liquid Chromatography (HPLC), ensuring drug safety and efficacy.
  Structural analysis of protein-based biologics: Directly analyzes the secondary and tertiary structural motifs of monoclonal antibodies, recombinant insulin, etc., in solution, and monitors their structural integrity and stability.
  VLP structure verification in vaccines: Analyzes the chiral structure and assembly status of Virus-Like Particles (VLPs) contained in HPV vaccines, etc., without damaging samples, to ensure vaccine immunogenicity.
  Chiral catalyst performance evaluation: Monitors the chiral structure changes of chiral catalysts such as organometallic complexes during reactions, determines the enantiomeric excess of products, and optimizes synthesis parameters.
  Structural consistency evaluation of biosimilars and originator drugs: Compares and analyzes the chiral structural motifs of biosimilars and originator drugs, providing data support for their clinical approval and quality control.
  Specification
  
  

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• 产品特色

  因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。

• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。