Deformability cytometry

• 详细介绍
• 详细参数

• 详细介绍

  Product Summary
  Naiad is a standalone device for researchers who need a tool to conduct deformability cytometry for the physical phenotyping of cells.
  Naiad is designed for high-speed imaging of cells as they flow through a microfluidic channel. It guarantees a frame rate higher than 3000 frames per second and maintains a stable and quantifiable flow rate, allowing for accurate and reliable cell analysis. Naiad is ideal for day-to-day research projects or long-term clinical studies.
  CytoShot software is used to operate the Naiad from a Windows or Mac computer.
  Advantage：
  We produce devices and software for the analysis of physical properties of cells, including their stiffness, size, shape and morphological features.
  Why do the mechanical properties of cells matter?
  Cell mechanics and other physical properties of cells reflect physiological and pathological changes in cell function. They are promising biomarkers for disease diagnosis and prognosis. For example, we recently found dramatic changes of blood cell mechanics during COVID-19.
  An HL-60 cell deforming under shear stress in a microfluidic channel. Video by MPL, licensed CC0.
  What is physical phenotyping of cells?
  Physical phenotyping involves the characterization of single living cells by their physical and morphological features such as size, shape and stiffness. An efficient technique for doing this is deformability cytometry. As a label-free method based purely on brightfield images of cells, deformability cytometry adds a new functional and unbiased dimension to flow cytometry. Combined with machine learning, deformability cytometry is a discovery machine for characterizing cell populations and functional states that are invisible to marker-based techniques.
  
  What is deformability cytometry?
  In deformability cytometry, thousands of single cells flow quickly through a narrow microfluidic channel, where the cells deform due to the forces applied. An image of each cell is taken and analyzed. Cell deformability and other parameters describing the cell's physical phenotype are extracted from the image. Thanks to high-speed video microscopy, our analysis rates of 1000 cells per second approach those of conventional fluorescence-based flow cytometers. Hundreds of thousands of cells are measured within minutes.
  Scheme of the microfluidic chip used for deformability cytometry
  Which samples can be analyzed?
  Any cell suspension can be measured with deformability cytometry - blood and other liquid biopsies, cells from solid tissues, and cultured cells. All of this is possible without time- and material-consuming sample preparation such as staining. As such, deformability cytometry supports diverse applications in biology, biotechnology and medicine.
  
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  Application
  
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• 产品特色

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  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。

• 详细介绍

  AutoCal系统提供在线的机器人校准方案，旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容，AutoCal系统可以检测出机器人自身构造和工具中心点（TCP）的 突然改变或偏离，并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错，不用浪费宝贵时间在机器人程序重复校准上，产品品质无任何损失。

  AutoCal系统-Dynalog的先进水平校准技术，Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统，被应用于离线的机器人单元校准，并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中，该系统专为程序控制和复原而设计的，价格低廉。